Results 51 to 60 of about 98,285 (300)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Evaluating the impact of annealing and radiative cooling on a PEGylated peptide formulation subjected to continuous spin-freeze-drying

AAPS Open
Annealing is commonly used in traditional lyophilization processes to crystallize solutes, improve drying efficiency and reduce cake heterogeneity, yet its integration into continuous spin-freeze-drying has not yet been reported.
Zarah Schaal, Pieter-Jan Van Bockstal, Joris Lammens, Julian H. Lenger, Adrian P. Funke, Stefan C. Schneid, Hristo L. Svilenov, Thomas De Beer   +7 more
doaj   +1 more source

Advance Drying Technology for Heat Sensitive Products [PDF]

, 2014
This book presents the advance drying technology for heat sensitive products cited from international journals, handbooks, and current research of authors. In the first edition, the printing and publication was funded Diponegoro University.
Djaeni, Mohamad, Suherman, Suherman, Sumardiono, Siswo   +2 more
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Study on the vacuum freeze-drying of banana and impact on powder properties

Case Studies in Thermal Engineering
This research evaluated vacuum freeze-drying (VFD) for banana slices in terms of drying behavior, energy, cost, color, rehydration, shrinkage, pH and °Brix, microstructure, and thermal images. Additionally, powder properties were investigated.
Onur Taskin
doaj   +1 more source

Effects of lipids on the water sorption, glass transition and structural strength of carbohydrate-protein systems [PDF]

, 2018
peer-reviewedEncapsulant systems are gaining wide practical interest due to their functional and nutritional properties. This paper was focusing on understanding structural relaxations in that systems near glass transition temperature.
Auty, Mark A., Lim, Aaron S. L., Maidannyk, Valentyn, Roos, Yrjô H.   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Multi-Point Wireless Temperature Sensing System for Monitoring Pharmaceutical Lyophilization

Frontiers in Chemistry, 2018
This work presents the design and evaluation of a fully wireless, multi-point temperature sensor system as a Process Analytical Technology (PAT) for lyophilization.
Xiaofan Jiang, Tong Zhu, Tatsuhiro Kodama, Nithin Raghunathan, Alina Alexeenko, Dimitrios Peroulis   +5 more
doaj   +1 more source

Use of Highly Dispersed Silica in Biotechnology of Complex Probiotic Product Based on Bifidobacteria

Innovative Biosystems and Bioengineering, 2022
Background. The probiotics immobilization technology is one of the most effective ways for controlled and continuous delivery of viable cells into the intestine.
Svitlana Danylenko , Lolita Marynchenko, Viktoriia Bortnyk, Oksana Potemska, Olena Nizhelska   +4 more
doaj   +1 more source

The effect of sample drying temperature on marine particulate organic carbon composition [PDF]

, 2018
Author Posting. © The Author(s), 2018. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution.
Galy, Valier, Johnson, Carl G., Lam, Phoebe J., McNichol, Ann P., Rosengard, Sarah Z.   +4 more
core   +1 more source