Results 41 to 50 of about 2,847,157 (340)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Promoting structured participation for competitiveness in services companies

open access: yesJournal of Industrial Engineering and Management, 2018
Purpose: To identify the main drivers that facilitate the successful deployment of a participation program aimed at improving competitiveness, as a prior step to analyze and discuss the implementation of these drivers in three services companies. Design/
Jesús García-Arca   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reducing Unplanned Readmissions in Pediatric Hospitals: Applying Patient and Family-Centered Care [PDF]

open access: yesGlobal Journal on Quality and Safety in Healthcare, 2023
Muhammad Hasan Abid
doaj   +1 more source

Export of miRNAs from activated macrophages is cooperative and HuR‐dependent

open access: yesFEBS Letters, EarlyView.
This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh   +2 more
wiley   +1 more source

Framework for Continuous Assessment and Improvement of Occupational Health and Safety Issues in Construction Companies

open access: yesSafety and Health at Work, 2014
Background: Construction industry is among the most hazardous industries, and needs a comprehensive and simple-to-administer tool to continuously assess and promote its health and safety performance. Methods: Through the study of various standard systems
Shahram Mahmoudi   +3 more
doaj   +1 more source

JOTSE'S New challenges and continuous improvement

open access: yesJournal of Technology and Science Education, 2020
As usual in JOTSE, the first editorial of the year presents an analysis of our Journal evolution. In this sense, we reflect on the changes just undergone and the challenges to be faced in the New Year 2020.
Beatriz Amante García   +1 more
doaj   +1 more source

Ready Educators Quality Improvement Pilot: Linking Program Improvement to Child Outcomes [PDF]

open access: yes, 2014
This report is an evaluation of the first year of the Ready Educators Quality Improvement Pilot (REQIP), part of Thrive in 5's city-wide Ready Educators strategy. The pilot provided technical assistance and support to early education and care programs in
Nancy L. Marshall
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Enablers and inhibitors for sustainability of continuous improvement: A study in the automotive industry suppliers in the Valencia Region

open access: yesIntangible Capital, 2009
In recent years it has been widely discussed the use of continuous improvement in all kind of business and particularly in companies belonging to the automotive industry.
Julio J. Garcia-Sabater   +1 more
doaj   +1 more source

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