Results 1 to 10 of about 3,548,556 (210)

Pharmacokinetics of imipenem in critically ill patients: Continuous infusion versus extended infusion in a real-world study [PDF]

Journal of International Medical Research
Objective This study compared the pharmacokinetic/pharmacodynamic properties of extended infusion and continuous infusion of imipenem at equivalent daily doses in a real-world setting.
Ruixia Zhang, Yi Qin, Yayao Lv, Yi Zhang
doaj   +2 more sources

Rationale and Logistics of Continuous Infusion Cephalosporin Antibiotics [PDF]

Pharmacy
Cephalosporins have traditionally been administered as an intermittent infusion. With the knowledge that cephalosporins demonstrate a time-dependent pharmacodynamic profile, administration via continuous infusion may provide more effective antibiotic ...
Abbie L. Blunier, R. Jake Crocker, Rachel Foster, Stephanie S. May, Caroline E. Powers, P. Brandon Bookstaver   +5 more
doaj   +2 more sources

Clinical efficacy of Endostar continuous infusion combined with concurrent chemoradiotherapy in the treatment of oesophageal squamous cell carcinoma [PDF]

Frontiers in Medicine
ObjectiveTo evaluate the effectiveness and safety of concurrent chemoradiotherapy using Endostar continuous infusion for treating oesophageal squamous cell carcinoma (OSCC).MethodA total of 62 patients with oesophageal carcinoma were divided into three ...
Xinglong Du, Yuting Ji, Wenqiang Qin, Jie Wei   +3 more
doaj   +2 more sources

Effectiveness of Extended or Continuous vs. Bolus Infusion of Broad-Spectrum Beta-Lactam Antibiotics for Febrile Neutropenia: A Systematic Review and Meta-Analysis

Antibiotics, 2023
This systematic review aimed to compare extended infusion or continuous infusion with bolus infusion for febrile neutropenia (FN). We included clinical trials comparing extended or continuous infusion with bolus infusion of beta-lactam antibiotics as ...
Kazuhiro Ishikawa, Koko Shibutani, Fujimi Kawai, Erika Ota, Osamu Takahashi, Nobuyoshi Mori   +5 more
doaj   +1 more source

Continuous wound infusion as an alternative to continuous epidural infusion for postoperative analgesia in renal transplant surgery: A prospective randomized controlled trial

Indian Journal of Transplantation, 2021
Background: Pain management is often challenging in patients undergoing renal transplant owing to the various comorbidities. Epidural analgesia is currently the standard technique but is not without complications.
Vinitha Narayan, Sameer Sethi, Kamal Kajal, Sarbpreet Singh   +3 more
doaj   +1 more source

Sedation Effects Produced by a Ciprofol Initial Infusion or Bolus Dose Followed by Continuous Maintenance Infusion in Healthy Subjects: A Phase 1 Trial

Advances in Therapy, 2021
The effects of continuous infusions of ciprofol on its pharmacodynamic and pharmacokinetic properties and safety profiles in healthy Chinese subjects were evaluated.
Chao Hu, X. Ou, Yi Teng, Shi-qing Shu, Ying Wang, Xiao-hong Zhu, Yan Kang, J. Miao   +7 more
semanticscholar   +1 more source

Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers

Anesthesiology, 2020
Background: Remimazolam (CNS 7056) is a new ultra–short-acting benzodiazepine for intravenous sedation and anesthesia. Its pharmacokinetics and pharmacodynamics have been reported for bolus administration.
J. Schüttler, Andreas Eisenried, M. Lerch, J. Fechner, C. Jeleazcov, H. Ihmsen   +5 more
semanticscholar   +1 more source

Continuous IV infusion of anakinra

Frontiers in Pharmacology, 2023
Objective: A review of the use of continuous IV infusion of anakinra; a description of the protocol for continuous IV infusion of anakinra in the treatment of cytokine storm developed over the past 4 years at a tertiary level academic medical center in ...
Brittney N. Saunders, Marcela V. Kuijpers, Jason J. Sloan, Elie Gertner   +3 more
doaj   +1 more source

Optimizing Betalactam Clinical Response by Using a Continuous Infusion: A Comprehensive Review

Antibiotics, 2023
Introduction: Antimicrobial resistance is a major healthcare issue responsible for a large number of deaths. Many reviews identified that PKPD data are in favor of the use of continuous infusion, and we wanted to review clinical data results in order to ...
Sylvain Diamantis, Catherine Chakvetadze, Astrid de Pontfarcy, Matta Matta   +3 more
doaj   +1 more source

Continuous Piperacillin-Tazobactam Infusion Improves Clinical Outcomes in Critically Ill Patients with Sepsis: A Retrospective, Single-Centre Study

Antibiotics, 2022
Continuous infusion of beta-lactam antibiotics has emerged as an alternative for the treatment of sepsis because of the favourable pharmacokinetics of continuous infusion. This study aimed to evaluate the survival benefits of continuous vs.
Dong-gon Hyun, Jarim Seo, Su Yeon Lee, Jee Hwan Ahn, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh   +7 more
doaj   +1 more source