Results 21 to 30 of about 5,232,603 (249)

Predictive Model-Based Process Start-Up in Pharmaceutical Continuous Granulation and Drying

Pharmaceutics, 2020
Continuous manufacturing (CM) is a promising strategy to achieve various benefits in the context of quality, flexibility, safety and cost in pharmaceutical production.
Victoria Pauli, Peter Kleinebudde, Markus Krumme   +2 more
doaj   +1 more source

Impact of Vertical Blender Unit Parameters on Subsequent Process Parameters and Tablet Properties in a Continuous Direct Compression Line

Pharmaceutics, 2022
The continuous manufacturing of solid oral-dosage forms represents an emerging technology among the pharmaceutical industry, where several process steps are combined in one production line.
Marius J. Kreiser, Christoph Wabel, Karl G. Wagner   +2 more
doaj   +1 more source

Lubricant Sensitivity of Direct Compression Grades of Lactose in Continuous and Batch Tableting Process

Pharmaceutics, 2023
Modern pharmaceutical manufacturing based on Quality by Design and digitalisation is revolutionising the pharmaceutical industry. Continuous processes are promoted as they increase efficiency and improve quality control.
Gerald A. Hebbink, Pauline H. M. Janssen, Jurjen H. Kok, Lorenzo Menarini, Federica Giatti, Caterina Funaro, Salvatore Fabrizio Consoli, Bastiaan H. J. Dickhoff   +7 more
doaj   +1 more source

Influence of enzymes with different activity on dynamics of buffalo milk coagulation parameters

Agricultural Science and Technology, 2020
: The aim of the present study was to evaluate the effect of 5 species of chymosin with different concentrations on the dynamics of the traits measured by mechanical lactodynamograph, characterizing the coagulation ability of buffalo milk.
Y. Karacheviev, V. Galabov, Т. Аngelova , D. Yordanova, V. Karabashev   +4 more
doaj   +1 more source

Comparison of the process mass intensity (PMI) of a continuous manufacturing process with batch manufacturing processes for biologics.

New Biotechnology, 2022
Biologics encompasses a wide variety of therapeutics including monoclonal antibodies, fusion proteins, and enzymes, among others. The biologics market is increasing at a rapid pace and different manufacturing processes, including continuous manufacturing
Srinivas Madabhushi, Nuno D. S. Pinto, Henry Lin   +2 more
semanticscholar   +1 more source

Nucleation and Growth Kinetics of Sodium Chloride Crystallization from Water and Deuterium Oxide

Crystals, 2023
Despite the ubiquity of the crystallization of sodium chloride (NaCl) throughout history, few detailed, well-controlled quantitative studies of the kinetics of NaCl crystallization have been published.
James M. Flannigan, Daniel MacIver, Hikaru Jolliffe, Mark D. Haw, Jan Sefcik   +4 more
doaj   +1 more source

Continuous Pharmaceutical Manufacturing

Pharmaceutics, 2020
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Ossi Korhonen
doaj   +1 more source

Continuous Isolation of Particles with Varying Aspect Ratios up to Thin Needles Achieving Free-Flowing Products

Crystals, 2022
The continuous vacuum screw filter (CVSF) for small-scale continuous product isolation of suspensions was operated for the first time with cuboid-shaped and needle-shaped particles.
Claas Steenweg, Jonas Habicht, Kerstin Wohlgemuth   +2 more
doaj   +1 more source

Integrated Continuous Wet Granulation and Drying: Process Evaluation and Comparison with Batch Processing

Pharmaceutics, 2023
The pharmaceutical industry is in the midst of a transition from traditional batch processes to continuous manufacturing. However, the challenges in making this transition vary depending on the selected manufacturing process.
Seth P. Forster, Erin Dippold, Abbe Haser, Daniel Emanuele, Robin Meier   +4 more
doaj   +1 more source

Loss-in-Weight Feeding, Powder Flow and Electrostatic Evaluation for Direct Compression Hydroxypropyl Methylcellulose (HPMC) to Support Continuous Manufacturing.

International journal of pharmaceutics, 2021
Minimizing variability in the feeding process is important for continuous manufacturing since materials are fed individually and can impact the final product.
Carl T. Allenspach, P. Timmins, G. Lumay, J. Holman, T. Minko   +4 more
semanticscholar   +1 more source