Results 131 to 140 of about 11,782,726 (286)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Fryer marketing: Economies of continuous and batch systems compared in Hayward area

California Agriculture, 1952
Producers of chicken fryers in the Hayward area of Alameda County have a wide range of outlets through which their fryers can reach consumers.
J Abbott
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Vibration of Continuous Systems

Shock and Vibration, 2010
Isaac Elishakoff
doaj   +1 more source

Novel application of magnetic nano-carbon composite as redox mediator in the reductive biodegradation of iopromide in anaerobic continuous systems. [PDF]

Appl Microbiol Biotechnol, 2018
Toral-Sánchez E, Rangel-Mendez JR, Hurt RH, Ascacio Valdés JA, Aguilar CN, Cervantes FJ.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Towards Continuous Improvement: Evolution, Drivers and Performance. Results of the 2nd International Continuous Improvement Survey

, 2005
Today there is a plenty of literature on Continuous Innovation: CI started ages ago, first in the USA, then in Japan. Notwithstanding this fact, little is known about Continuous Innovation in other continents: more exactly little is known about ...
GIACOBBE A, CORSO M, MARTINI, ANTONELLA, PELLEGRINI, LUISA   +3 more
core  

Biohydrogen production from enzymatic hydrolysis of food waste in batch and continuous systems. [PDF]

Sci Rep, 2016
Han W, Yan Y, Shi Y, Gu J, Tang J, Zhao H.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Nonvariational Elliptic Systems

, 2015
In this paper, we present new concepts of sublinearity and super-linearity for elliptic systems of the form (P) {-Δu = f(u, v), - Δv = g(u,v) in Ω u = v = 0 on ∂Ω where Ω is a smooth bounded domain and f,g are continuous functions.
Alves C.O., De Figueiredo D.G.
core