Results 71 to 80 of about 11,782,726 (286)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Polynomial and linearized normal forms for almost periodic differential systems [PDF]
, 2016 Agraïments: The first author is partially supported by NSFC key program of China (no. 11231001). The MINECO/FEDER grant UNAB13-4E-1604. And the third is supported by NSFC for Young Scientists of China (no.
Wu, Hao, Llibre, Jaume, Li, Weigu
core +1 more source
Alternate-continuous-control systems with double-impulse
Advances in Difference Equations, 2017 We propose a mathematical model that can control the stability of an unstable system. Periodicity is an important feature of the system. We add a continuous control to the first half of each period of the system and then add an impulse control J1 at the ...
Xiang Hu +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Continuous Dependence of Attractors on Parameters of Non-Autonomous Dynamical Systems and Infinite Iterated Function Systems [PDF]
, 2007 The paper is dedicated to the study of the problem of continuous dependence of compact global attractors on parameters of non-autonomous dynamical systems and infinite iterated function systems (IIFS).
MAMMANA, Cristiana, D. CHEBAN
core
Indefinite causal structures for continuous-variable systems
New Journal of Physics, 2016 In all our well-established theories, it is assumed that events are embedded in a global causal structure such that, for every pair of events, the causal order between them is always fixed.
Flaminia Giacomini +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Continuous symmetry defects and brane/anti-brane systems
Journal of High Energy PhysicsWe explicitly compute correlation functions with the insertion of a continuous symmetry defect in bosonic field theories. To recover its expected action on the charged operators, the definition of the defect must be modified to include a specific contact
Hugo Calvo +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source