Results 31 to 40 of about 6,090 (261)
Micro-macro mechanics of damage and healing in rocks
Open Geomechanics, 2021 This paper presents the state of the art of the theory of damage and healing mechanics, with a particular emphasis on the strategies available to relate the micro-scale of crystals, cracks and pores to the scale of a Representative Elementary Volume ...
Chloé Arson
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A Generalized Hypothesis of Elastic Energy Equivalence in Continuum Damage Mechanics
Engineering Transactions, 2017 A new generalized hypothesis of elastic energy equivalence is proposed. The proposed generalized hypothesis is inclusive of all the existing different hypotheses of equivalence in continuum damage mechanics and all are obtained as special cases ...
George Z. VOYIADJIS, Peter I. KATTAN
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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Engineering Transactions, 2003 The main goal of this paper is to present a computational analysis of damage evolution in adhesive joint connecting composite pipes subjected to cyclic static axial tension with constant amplitude.
Ł. Figiel, M. Kamiński
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Strain capacity assessment of API X65 steel using damage mechanics [PDF]
Fracture and Structural Integrity, 2017 Strain-based design for offshore pipeline requires a considerable experimental work aimed to determine the material fracture toughness and the effective strain capacity of pipe and welds.
Gabriel Testa +6 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source