Results 51 to 60 of about 2,435,415 (320)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Research in the development of finite element software for creep damage analysis [PDF]

open access: yes, 2013
This paper reports the development of finite element software for creep damage analysis. Creep damage deformation and failure of high temperature structure is a serious problem for power generation and it is even more technically demanding under the ...
Xu, Qiang, Liu, Dezheng, Lu, Zhongyu
core   +3 more sources

A non-local continuum poro-damage mechanics model for hydrofracturing of surface crevasses in grounded glaciers

open access: yesJournal of Glaciology, 2020
Hydrofracturing can enhance the depth to which crevasses propagate and, in some cases, allow full depth crevasse penetration and iceberg detachment.
R. Duddu, S. Jiménez, J. Bassis
semanticscholar   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Numerical Analysis of the Damage Evolution in a Composite Pipe Joint Under Cyclic Static Axial Tension

open access: yesEngineering Transactions, 2003
The main goal of this paper is to present a computational analysis of damage evolution in adhesive joint connecting composite pipes subjected to cyclic static axial tension with constant amplitude.
Ł. Figiel, M. Kamiński
doaj   +1 more source

Parametrically homogenized continuum damage mechanics (PHCDM) models for composites from micromechanical analysis

open access: yesComputer Methods in Applied Mechanics and Engineering, 2019
This paper develops a parametrically homogenized continuum damage mechanics (PHCDM) model for unidirectional fiber-reinforced composites undergoing progressive damage.
Xiaofan Zhang   +3 more
semanticscholar   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Statistical microdamage mechanics and damage field evolution

open access: yes, 2001
Discussed are the underlying background of statistical microdamage mechanics, the fundamental partial differential equation of evolution of microdamage number density, two basic solutions, and the saturation of microdamage number density evolution ...
Bai, YL (reprint author), Chinese Acad Sci, Inst Mech, LNM, State Key Lab Nonlinear Mech, Beijing 100080, Peoples R China.   +4 more
core   +1 more source

Coupling crystal plasticity and continuum damage mechanics for creep assessment in Cr-based power-plant steel

open access: yesMechanics of materials (Print), 2019
To improve the design and safety of power plant components, long-term high-temperature creep behaviour of a power-plant material, such as Cr-based alloy, should be assessed.
Nai-Long Zhao   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy