Results 41 to 50 of about 89,082 (299)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Literature study report of plasticity induced anisotropic damage modeling for forming processes [PDF]
A literature study report covering the topics; micromechanics of damage, continuum damage mechanics (gurson model and effective variable concept) and the dependence of damage on strain rate and ...
Niazi, M.S.
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The main goal of this paper is to present a computational analysis of damage evolution in adhesive joint connecting composite pipes subjected to cyclic static axial tension with constant amplitude.
Ł. Figiel, M. Kamiński
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Strain capacity assessment of API X65 steel using damage mechanics [PDF]
Strain-based design for offshore pipeline requires a considerable experimental work aimed to determine the material fracture toughness and the effective strain capacity of pipe and welds.
Gabriel Testa +6 more
doaj +2 more sources
Phenomenological modeling of strain hardening, phase transformation and damage effects of trip-steels [PDF]
In this study, the constitutive modeling of loading state dependent strain hardening and martensite evolution of high alloyed TRIP-steels are addressed, which are experimentally observed comparing uni-axial tension and compression test results ...
Kuna, Meinhard, Seupel, Andreas
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Preliminary analysing of experimental data for the development of high Cr Alloy Creep damage Constitutive Equations [PDF]
This conference paper presents the current research of preliminary analysing of experimental data for the development of high Cr Alloy Creep damage Constitutive Equations (such as P91 alloy). Firstly, it briefly introduces the background of general creep
An, Lili +3 more
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