Results 61 to 70 of about 89,082 (299)
New methodology for calculating damage variables evolution in Plastic Damage Model for RC structures [PDF]
, 2017 The behavior of reinforced concrete (RC) structures under severe demands, as strong ground motions, is highly complex; this is mainly due to joint operation of concrete and steel, with several coupled failure modes.
Alfarah, Bashar +2 more
core +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Analysis of Damage Value of Aluminum Alloys—Application of a Continuum Damage Mechanics Model
Applied MechanicsDamage refers to the degradation of a material subjected to an external condition such as loading, temperature, and environment. Several investigations have been undertaken to understand the damage of materials like steel, aluminum alloy, titanium alloy,
Vishavbandhu Kanwar +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Geofluids, 2021 The effect of the bedding structure on the mechanical properties of layered shale was studied by means of experiment and numerical simulation. Based on continuum damage theory and discrete fracture network modeling method (D-DFN), a finite element model ...
Qinglin Shan +4 more
doaj +1 more source
Multiscale computational first order homogenization of thick shells for the analysis of out-of-plane loaded masonry walls [PDF]
, 2017 This work presents a multiscale method based on computational homogenization for the analysis of general heterogeneous thick shell structures, with special focus on periodic brick-masonry walls.
Camata, Guido +5 more
core +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Damage mechanics : basic variables in continuum theories
International Journal of Solids and Structures, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cauvin, Alix, Testa, Rene B.
openaire +1 more source
A physics-based life prediction methodology for thermal barrier coating systems
, 2007 A novel mechanistic approach is proposed for the prediction of the life of thermal barrier coating (TBC) systems. The life prediction methodology is based on a criterion linked directly to the dominant failure mechanism.
Busso, Esteban +6 more
core +3 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source