Results 101 to 110 of about 226,240 (293)
Nihon Kikai Gakkai ronbunshu, 2018 In this paper, a new formulation for computing ΔJ using the three-dimensional equivalent domain integral method for finite deformation elastic-plastic problem is presented.
Koichiro ARAI +2 more
doaj +1 more source
Two-integral distribution functions for axisymmetric stellar systems with separable densities
, 2008 We show different expressions of distribution functions (DFs) which depend only on the two classical integrals of the energy and the magnitude of the angular momentum with respect to the axis of symmetry for stellar systems with known axisymmetric ...
Jiang, Zhenglu, Ossipkov, Leonid
core +2 more sources
Contour integration in anisometropic amblyopia
Vision Research, 1998 Contour integration was measured in a group of anisometropic amblyopes to test the idea recently put forward that positional uncertainty sets a fundamental limit to contour integration in amblyopia. Anisometropic amblyopia, unlike strabismic amblyopia, has little or no positional uncertainty once the initial filtering loss has been taken into account ...
Hess, Robert F., Demanins, Rita
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 2005 The invention of the "dual resonance model" N-point functions BN motivated the development of current string theory. The simplest of these models, the four-point function B4, is the classical Euler Beta function. Many standard methods of complex analysis
Andrew J Hanson +20 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source