Results 111 to 120 of about 43,956 (257)

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado, Bernardo Fontel Pompeu, Vinícius dos Santos Macedo, Gabriel Henrique Acedo Martins, Eric Pasqualotto, Matheus Reginato Araujo, Julia Hoici Brunini, Victor Andrade Nunes, Cláudia Theis, Samuel Aguiar Junior   +9 more
wiley   +1 more source

Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos, Line Kibsgaard, Trine Bertelsen   +2 more
wiley   +1 more source

Time‐dependent wound management protocol prevents periprosthetic joint infection in total knee arthroplasty with persistent drainage

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the success rate of a standardised protocol for managing persistent wound drainage following total knee arthroplasty (TKA). Methods A prospective observational study was conducted at four institutions between January and June 2022 across primary and revision TKAs.
Filippo Leggieri, Francesco Ferriani, Enrico Di Benedetto, Enrick Miani, Enrico Festa, Giovanni Balato, Stefano M. P. Rossi, Francesco Benazzo, Andrea Baldini   +8 more
wiley   +1 more source

Bridging the Ideological Divide: Advertising Strategies for Promoting Stigmatized Products

Psychology &Marketing, EarlyView.
ABSTRACT Many socially relevant sexual and reproductive health products remain stigmatized by some consumers due to enduring socio‐cultural taboos, despite broader acceptance by others. Such stigma limits product adoption and poses public health risks.
Yunlu Zhao, Verdiana Giannetti, Evangelia Mavroudi, Dayananda Palihawadana   +3 more
wiley   +1 more source

Contraceptives in chronic lymphocytic leukemia (CLL): a narrative review. [PDF]

Ann Hematol
Al-Shibly R, Qassim N, Alfarsi K, AlShemmari S, Yassin M.   +4 more
europepmc   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Evidence on the Reasons and Factors Influencing Contraceptive Nonutilization Among Women of Childbearing Age in Suburban Setting in Sub-Saharan Africa: A Scoping Review. [PDF]

Nurs Health Sci
Baloyi TV, Madela-Mntla E, Duah E, Maluleke K, Kgarosi K, Pieters J, Mashamba-Thompson T.   +6 more
europepmc   +1 more source

Underlying Mechanisms of the Treatment Efficacy of (R, S)‐Ketamine for Post‐Traumatic Stress Disorder and Depression: A Review

Medicine Advances, EarlyView.
Research shows that (R, S)‐ketamine and its stereoisomers effectively reduce symptoms of post‐traumatic stress disorder (PTSD) and treatment‐resistant depression, with (R)‐ketamine offering similar benefits with fewer side effects. Evidence highlights specific neural circuits and regions, including the dentate gyrus, prefrontal cortex, vCA3, dorsal ...
Thomas Edward Cutting, Richard Evans Hartman   +1 more
wiley   +1 more source

Unsafe Sex, AIDS, and Development [PDF]

Much of Africa has been ravaged by the AIDS epidemic. There, heterosexual contact is the primary mode of transmission for the HIV virus. Even when access to condoms is good and their price low, a large fraction of young Africans continue to engage in ...
Bhattacharya, Joydeep, Bunzel, Helle, Qiao, Xue   +2 more
core  

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source