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Pharmacologic Development of Male Hormonal Contraceptive Agents [PDF]

open access: yesClinical Pharmacology & Therapeutics, 2010
The world population continues to increase dramatically despite the existence of contraceptive technology. The use of male hormonal contraception may help in preventing un intended pregnancies and managing future population growth. Male hormonal contraception relies on the administration of exogenous hormones to suppress spermatogenesis.
M Y, Roth, J K, Amory
openaire   +3 more sources

Hormonal Male Contraception: Getting to Market

open access: yesFrontiers in Endocrinology, 2022
Rates of unplanned pregnancies are high and stagnant globally, burdening women, families and the environment. Local limitations placed upon contraceptive access and abortion services exacerbate global disparities for women. Despite survey data suggesting
Stephanie T. Page   +2 more
doaj   +2 more sources

A Critical Review and Scientific Prospective on Contraceptive Therapeutics from Ayurveda and Allied Ancient Knowledge

open access: yesFrontiers in Pharmacology, 2021
Commonly used synthetic or prescribed hormonal drugs are known to interfere with the endocrine system and may have adverse reproductive, neurological, developmental, and metabolic effects in the body.
Narendra Bhatt, Manasi Deshpande
doaj   +2 more sources

“Cassia auriculata-derived silver nanoparticles as a novel male contraceptive agent”

open access: yesPharmacological Research - Modern Chinese Medicine
Introduction: The development of male contraception remains a crucial area of research in reproductive health. Nanotechnology offers innovative solutions, with plant-derived nanoparticles emerging as potential antifertility agents.
Prity Yadav   +3 more
doaj   +2 more sources

A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse

open access: yesBioactive Materials, 2021
Current contraceptive methods come with a number of drawbacks, including low efficacy, in the case of commercial contraceptive gels, and a reduction in the quality of sexual intercourse, in the case of condoms.
Mengjie Xie   +9 more
doaj   +1 more source

Trends and Determinants of Family Planning Utilization Among Men in Indonesia

open access: yesMakara Journal of Health Research, 2021
Background: Population growth rate in the world is still increasing. To control population growth, governments issue family planning programs for married women and men. However, contraception use is still dominated by women.
Haerawati Idris, Willyana Syafriyanti
doaj   +1 more source

Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates [PDF]

open access: yesNature Communications, 2021
Abstract There are no non-hormonal male contraceptives currently on the market despite decades of efforts toward the development of “male pills”. Here, we report that triptonide, a natural compound purified from the Chinese herb Tripterygium Wilfordii Hook F displays ...
Zongliang Chang   +20 more
openaire   +5 more sources

Size‐Dependent Inhibition of Sperm Motility by Copper Particles as a Path toward Male Contraception

open access: yesAdvanced NanoBiomed Research, 2022
Effective inhibition of sperm motility using a spermicide can be a promising approach in developing non‐invasive male contraceptive agents. Copper is known to have contraceptive properties and has been used clinically for decades as intrauterine ...
Purnesh Chattopadhyay   +5 more
doaj   +1 more source

“Antibiotics Can Work as a Contraceptive:” Contraceptive Knowledge and Use Among University Students in Calabar, Nigeria

open access: yesFrontiers in Reproductive Health, 2021
Introduction: Many sexually active youths who wish to delay pregnancy are not using any form of modern contraceptives. In sub-Saharan Africa, less than 1 in 5 sexually active youth do not use contraceptives.
Ibitola Asaolu   +8 more
doaj   +1 more source

Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine

open access: yesACS Omega, 2023
There is a huge demand for safe and effective non-hormonal male contraceptives to prevent unintended pregnancy, but research on male contraceptive drugs lacks far behind the pills for women. Lonidamine and its analog adjudin are two of the best studied potential male contraceptives.
Shengnan Gong   +6 more
openaire   +2 more sources

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