Results 11 to 20 of about 11,471 (198)
Pharmaceutics, 2022 Despite the vast amounts of research and remarkable discoveries that have been made in recent decades, cancer remains a leading cause of death and a major public health concern worldwide.
Dilipkumar Pal +4 more
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Effects of Boron-Containing Compounds on Liposoluble Hormone Functions
Inorganics, 2023 Boron-containing compounds (BCC), particularly boronic acids and derivatives, are being increasingly tested as diagnostic and therapeutic agents. Some effects of BCC involve phenomena linked to the action of steroid or thyroid hormones; among these, are ...
Elizabeth Estevez-Fregoso +6 more
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Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine
ACS Omega, 2023 There is a huge demand for safe and effective non-hormonal male contraceptives to prevent unintended pregnancy, but research on male contraceptive drugs lacks far behind the pills for women. Lonidamine and its analog adjudin are two of the best studied potential male contraceptives.
Shengnan Gong +6 more
openaire +2 more sources
Rising trends towards the development of oral herbal male contraceptive: an insight review
Future Journal of Pharmaceutical Sciences, 2021 Background Acknowledging population control to be an essential step for global health promotes wide research study in the area of male contraception. Although there are a great number of synthetic contraceptives available in the market, they have plenty ...
Surender Verma, Akash Yadav
doaj +1 more source
Trials, 2021 Objectives As of December, 1st, 2020, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2, resulted in more than 1 472 917 deaths worldwide and death toll is still increasing exponentially.
W. Dioh +15 more
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Escherichia coli recombinant sperm immobilizing factor RecX as a potential vaginal contraceptive
Reproductive Biology and Endocrinology, 2018 Background To control the overpopulation and unintended pregnancies, vaginal contraceptives have gained recent surge of interest because of its topical application with possible avoidance of systemic effects.
Monika Answal, Vijay Prabha
doaj +1 more source
RICOM: a potential male contraceptive agent?
The FASEB Journal, 2012 The minor seed variety of RICOM – 1013‐J, a local contraceptive agent among the Rukuba women of Central Nigeria was studied. The N‐hexane extract of RICOM has been shown to possess anti‐fertility properties in adult cyclic Sprague‐Dawley rats.
Rosie Thecla McNeil +4 more
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Gamendazole, an Orally Active Indazole Carboxylic Acid Male Contraceptive Agent, Targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and Stimulates Il1a Transcription in Rat Sertoli Cells1 [PDF]
Biology of Reproduction, 2008 Gamendazole was recently identified as an orally active antispermatogenic compound with antifertility effects. The cellular mechanism(s) through which these effects occur and the molecular target(s) of gamendazole action are currently unknown. Gamendazole was recently designed as a potent orally active antispermatogenic male contraceptive agent.
Joseph S. Tash +11 more
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Gates Open Research, 2019 Background: Male engagement is becoming more common in family planning (FP) strategies and interventions, yet effective monitoring and evaluation (M&E) of this approach lags. This review sought to understand how male engagement in FP is defined, identify
Bridgit M. Adamou +3 more
doaj +1 more source
The effect of the male contraceptive agent Gossypol on human lymphocytes in vitro: traditional chromosome breakage, micronuclei, sister chromatid exchange, and cell kinetics. [PDF]
Journal of Medical Genetics, 1983 The male antifertility agent Gossypol did not affect the level of traditional chromosome breakage or number of micronuclei in 66-hour lymphocyte cultures at concentrations up to 40 micrograms/ml. It did increase the frequency of SCE slightly, although the inter-individual variation was greater than the increase resulting from Gossypol, and, even at the
Y C, Tsui, M R, Creasy, M A, Hultén
openaire +2 more sources