TRPV4 regulates intraocular pressure through trabecular meshwork contractility and fibrosis. [PDF]
Žavbi J, Redmon SN, Križaj D.
europepmc +1 more source
The contractile activity of leukocyte contractile protein
Nobuhiko Shibata +2 more
openaire +2 more sources
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
The effect of intravenous calcium administration on haemodynamics in perioperative cardiothoracic surgery and intensive care: A narrative review. [PDF]
Miller A +6 more
europepmc +1 more source
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng +8 more
wiley +1 more source
Is Resynchronization Pacing Proarrhythmic Among Congenital Heart Patients? An Evaluation and Review. [PDF]
Karpawich PP +6 more
europepmc +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
OptoTAT reveals microtubule acetylation as a rapid trigger for GEF-H1-mediated cell migration. [PDF]
Deb Roy A +6 more
europepmc +1 more source
A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation [PDF]
et al,, Mann, Douglas L
core +1 more source

