Results 51 to 60 of about 4,671,855 (301)

Contrast-enhanced MRI for quantification of myocardial viability [PDF]

Journal of Magnetic Resonance Imaging, 1999
During the past 10 years substantial advances have taken place in magnetic resonance imaging (MRI) capabilities and in contrast media development. Furthermore, knowledge of in vivo contrast media interactions with surrounding water and distribution into tissue has increased, permitting regional quantification of concentration-time profiles in the ...
M F, Wendland, M, Saeed, G, Lund, C B, Higgins   +3 more
openaire   +2 more sources

Analysis of DCE-MRI Data using a Nonnegative Elastic Net [PDF]

, 2010
We present a nonnegative Elastic Net approach for the analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging data. A multi-compartment approach is considered, which is translated into a (restricted) least square model selection problem.
Gertheiss, Jan, Kärcher, Julia C., Schmid, Volker J.   +2 more
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Elemental imaging of MRI contrast agents: benchmarking of LA-ICP-MS to MRI

, 2012
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has been used to map the spatial distribution of magnetic resonance imaging (MRI) contrast agents (Gd-based) in histological sections in order to explore synergies with in vivo MRI ...
Bunch, J., Hart, S.L., White, E., Cox, A.G., Bienemann, A., McLeod, C.W., Bell, J.D., Writer, M.J., Pugh, J.A.T.   +8 more
core   +1 more source

Small-bowel MRI in children and young adults with Crohn disease: retrospective head-to-head comparison of contrast-enhanced and diffusion-weighted MRI [PDF]

, 2013
Small-bowel MRI based on contrast-enhanced T1-weighted sequences has been challenged by diffusion-weighted imaging (DWI) for detection of inflammatory bowel lesions and complications in patients with Crohn ...
Dick, Anke, Pabst, Thomas, Köstler, Herbert, Wirth, Clemens, Evangelista, Laura, Hahn, Dietbert, Machann, Wolfram, Neubauer, Henning, Beer, Meinrad   +8 more
core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Contrast enhanced magnetic resonance imaging of the foot in horses using intravenous versus regional intraarterial injection of gadolinium [PDF]

Open Veterinary Journal, 2018
The use of contrast enhanced magnetic resonance imaging (MRI) for the detection of orthopedic pathologies in equine patients is poorly described. In few studies, enhanced MRI allowed to differentiate active lesions from chronic ones and to classify ...
Donatella De Zani, Vanessa Rabbogliatti, Giuliano Ravasio, Cinzia Pettinato, Mauro Di Giancamillo, Davide Danilo Zani   +5 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

A comparative study between the diagnostic performance of contrast-enhanced digital mammography and dynamic contrast-enhanced MRI in invasive lobular carcinoma of the breast

The Egyptian Journal of Radiology and Nuclear Medicine
Background Invasive lobular carcinoma is the second most prevalent histological subtype of breast cancer after invasive duct carcinoma, with a reported increased incidence in the last two decades.
Sherihan Fakhry, Rasha Mohamed Kamal, Omnia Mokhtar Nada, Amira Emad Abo El Enien Mohamed, Mennatallah Mohamed Hanafy   +4 more
doaj   +1 more source

Contrast-Enhanced MRI of Rheumatic Joint Disease [PDF]

Rheumatology, 1996
Early MR diagnosis of inflammatory rheumatic joint disease relies on the detection of the proliferating synovium. Several studies have shown that reliable visualization of the inflamed synovium is dependent upon the enhancement provided by intravenously injected paramagnetic contrast media.
openaire   +2 more sources