Results 101 to 110 of about 6,785,321 (317)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Technical note: A simple and effective CO 2 delivery system for angiography using a blood bag

Indian Journal of Radiology and Imaging, 2009
Several angiographic techniques have been developed to image the arterial system, the commonest using iodinated contrast media. Useful as they may be, they are not without disadvantages. One other modality is angiography using CO 2 .
Mathew P Cherian, Pankaj Mehta, Prashant Gupta, Tejas M Kalyanpur, SR Jayesh, R Rupa   +5 more
doaj   +1 more source

Two improved forensic methods of detecting contrast enhancement in digital images [PDF]

, 2014
Contrast enhancements, such as histogram equalization or gamma correction, are widely used by malicious attackers to conceal the cut-and-paste trails in doctored images.
Xufeng Lin, Lin, Xufeng, Chang-Tsun Li, Xingjie Wei, Wei, Xingjie, Li, Chang-Tsun   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Revealing the Concealed in Monocular and Binocular Vision

Vision
Concealing images has been a concern of artists and scientists, as have the conditions that can reveal them. It is relatively easy to hide images in pictures, but this is of little value if they remain hidden.
Nicholas J. Wade
doaj   +1 more source

Perceived Blur in Naturally-Contoured Images Depends on Phase

Frontiers in Psychology, 2010
Perceived blur is an important measure of image quality and clinical visual function. The magnitude of image blur varies across space and time under natural viewing conditions owing to changes in pupil size and accommodation.
Stephanie Murray, Peter J Bex
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source