Results 91 to 100 of about 899,795 (311)

Enhanced microbubble contrast agent oscillation following 250 kHz insonation

open access: yesScientific Reports, 2018
Microbubble contrast agents are widely used in ultrasound imaging and therapy, typically with transmission center frequencies in the MHz range. Currently, an ultrasound center frequency near 250 kHz is proposed for clinical trials in which ultrasound ...
Tali Ilovitsh   +11 more
doaj   +1 more source

The Challenge of T1 Contrast Agents for High-Magnetic Field MRI

open access: yesCHIMIA, 2011
Magnetic resonance imaging (MRI) is one of the most powerful diagnostic techniques used in clinics. The need for higher spatial resolution and better sensitivity led to the development of imagers working at high magnetic fields.
Lothar Helm
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Alignment of contrast enhanced medical images

open access: yes, 2009
The re-alignment of series of medical images in which there are multiple contrast variations is difficult. The reason for this is that the popularmeasures of image similarity used to drive the alignment procedure do not separate the influence of ...
Melbourne, A.
core  

Fairness and Incentives in a Multi-Task Principal-Agent Model [PDF]

open access: yes, 2004
This paper reports on a two-task principal-agent experiment in which only one task is contractible. The principal can either offer a piece-rate contract or a (voluntary) bonus to the agent. Bonus contracts strongly outperform piece rate contracts.
Fehr, Ernst   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Magnetic resonance imaging and the development of vascular targeted treatments for cancer.

open access: yes, 2005
The main subject of the work presented in this thesis is the further development of magnetic resonance imaging (MRI) as a non-invasive method of investigating tumour microcirculation. Two different MR techniques were used: dynamic contrast enhanced (DCE)-
Lankester, K.J.
core  

EPR assessment of protein sites for incorporation of Gd(III) MRI contrast labels.

open access: yes, 2013
We have engineered apolipoprotein A-I (apoA-I), a major protein constituent of high-density lipoprotein (HDL), to contain DOTA-chelated Gd(III) as an MRI contrast agent for the purpose of imaging reconstituted HDL (rHDL) biodistribution, metabolism and ...
Alex I. Smirnov   +27 more
core   +1 more source

Subharmonic resonance of phospholipid coated ultrasound contrast agent microbubbles

open access: yesUltrasonics Sonochemistry
Phospholipid encapsulated ultrasound contrast agents have proven to be a powerful addition in diagnostic imaging and show emerging applications in targeted therapy due to their resonant and nonlinear scattering.
Hossein Yusefi, Brandon Helfield
doaj   +1 more source

The most appropriate time delay after microbubble contrast agent intravenous injection to maximize liver metastasis conspicuity on contrast-enhanced ultrasound

open access: yesJournal of Medical Ultrasound, 2018
Purpose: To identify the most appropriate time delay after microbubble contrast agent injection to maximize liver metastasis conspicuity on contrast-enhanced ultrasound (CEUS).
Emilio Quaia, Antonio Giulio Gennari
doaj   +1 more source

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