Results 71 to 80 of about 3,927,862 (312)
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Research Progresses in Development of Thermo-Sensitive MRI Contrast Agent
Magnetic resonance imaging (MRI) is a practical technique for non-invasive temperature measurement. Thermo-sensitive MRI contrast agents, which cause temperature-dependent changes in magnetic resonance parameters of water molecules (i.e., relaxation ...
LU Yao, ZHENG Xin-wei, ZHONG Kai
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An integrated trust and reputation model for open multi-agent systems
Trust and reputation are central to effective interactions in open multi-agent systems in which agents, that are owned by a variety of stakeholders, continuously enter and leave the system.
Jennings, N. R. +5 more
core +1 more source
Human-agent collaboration for disaster response [PDF]
In the aftermath of major disasters, first responders are typically overwhelmed with large numbers of, spatially distributed, search and rescue tasks, each with their own requirements.
Jiang, W +16 more
core +1 more source
How to Perform Cardiac Contrast-Enhanced Ultrasound (cCEUS): Part I
Ultrasound enhancing agents (UEAs, formerly called contrast agents) for assessments of the left heart have improved the applicability of echocardiography and the accuracy of echocardiographic measurements.
Harald Becher +5 more
doaj +1 more source
Gold-coated plant virus as computed tomography imaging contrast agent
Chemical modification of the surface of viruses, both the interior and the exterior, imparts new functionalities, that have potential applications in nanomedicine.
Alaa A. A. Aljabali +11 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Binocular contrast vision at and above threshold [PDF]
A fundamental problem for any visual system with binocular overlap is the combination of information from the two eyes. Electrophysiology shows that binocular integration of luminance contrast occurs early in visual cortex, but a specific systems ...
Georgeson, Mark A. +6 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

