Results 81 to 90 of about 3,927,862 (312)

Transient Cortical Blindness Following Coronary Angiography

JACC: Case Reports, 2019
Transient cortical blindness (TCB) is an uncommon complication following coronary angiography. This report describes a case of TCB after coronary angiography in a patient admitted for acute myocardial infarction. The patient’s vision recovered completely
Sara I.L. Fernandes, MD, Rita J.R. Carvalho, MD, Luís M.G. Santos, MD, Fernando M.P.M. Sá, MD, José A.S. Antunes, MD, Ana S.L. Mendes, MD, Joana S. Correia, MD, Maria F.A. Saraiva, MD, Hélia A.F. Martins, MD, João C.A. Morais, PhD   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Designing and Evaluating an Adaptive Trading Agent for Supply Chain Management Applications

, 2005
This paper describes the design and evaluation of SouthamptonSCM, a finalist in the 2004 Trading Agent Supply Chain Management Competition (TAC SCM). In particular, we focus on the way in which our agent sets its prices according to the prevailing market
David, E, He, Minghua, David, Esther, Jennings, N. R., Alex Rogers, Esther David, Nicholas R. Jennings, Rogers, A, Rogers, Alex, He, M, Jennings, NR, Minghua He   +11 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The functional role of contrast adaptation [PDF]

, 1988
Prolonged inspection of high contrast sinewave gratings increases the contrast required to detect gratings having a similar spatial frequency and orientation. The functional role of such adaptation has, however, in the past, eluded disclosure.
Heitger, F., Greenlee, Mark W.
core   +1 more source

Fluorescein- and EGFR-Antibody Conjugated Silica Nanoparticles for Enhancement of Real-time Tumor Border Definition Using Confocal Laser Endomicroscopy in Squamous Cell Carcinoma of the Head and Neck

Nanomaterials, 2019
Intraoperative definition of tumor free resection margins in head and neck cancer is challenging. In the current proof-of-principle study we evaluated a novel silica nanoparticle-based agent for its potential use as contrast enhancer.
Anna Watermann, Rita Gieringer, Anna-Maria Bauer, Sven Kurch, Ralf Kiesslich, Wolfgang Tremel, Jan Gosepath, Juergen Brieger   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

R_Contrast: Rapid measurement of recognition contrast thresholds. [PDF]

, 1997
R_Contrast is a program for the rapid assessment of recognition contrast thresholds on the ...
Strasburger, Hans, Hans Strasburger
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A low molecular weight folate receptor targeted contrast agent for magnetic resonance tumour imaging

, 2011
Purpose: This study aims to develop a low molecular weight folate receptor (FR) contrast agent for MR tumor imaging. Procedures: Gadolinium-tetraazacyclododecane tetraacetic acid (Gd.DOTA) was conjugated to folic acid to create Gd.DOTA.Folate.
Bunch, J., So, P.W., Jorgensen, M.R., Kamaly, N., McLeod, C.W., Bell, J.D., Pugh, J.A.T., Miller, A.D., Kalber, T.   +8 more
core   +1 more source