Results 91 to 100 of about 3,458,713 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Subprime Crisis and Instability of Global Financial Markets [PDF]

In order to prescribe adequate remedies to treat the current financial crisis one has to understand what in the first place went wrong. An age ago, older generations wrote that disease could not be cured without an accurate diagnosis.
Miodrag Zec, Ognjen Radonjić
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

P1-4: Neural Correlates of Fading Illusion Revealed in Responses of V1 Neurons

i-Perception, 2012
Visual stimuli without sharp edges fade gradually under visual fixation. This phenomenon is known as Troxler fading or fading illusion. Traditionally, this fading is explained by a hypothesis that physical stimulus is cancelled by a negative image ...
Kohei Kurihara, Kota S Sasaki, Izumi Ohzawa   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Theory of the perceived motion direction of equal-spatial-frequency plaid stimuli. [PDF]

, 2020
At an early stage, 3 different systems independently extract visual motion information from visual inputs. At later stages, these systems combine their outputs.
Lin, Ling, Liu, Dantian, Sperling, George, Sun, Peng   +3 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Face Attractiveness versus Artistic Beauty in Art Portraits: A Behavioral Study

Frontiers in Psychology, 2017
From art portraits, the observer may derive at least two different hedonic values: The attractiveness of the depicted person and the artistic beauty of the image that relates to the way of presentation.
Katharina Schulz, Gregor U. Hayn-Leichsenring, Gregor U. Hayn-Leichsenring, Gregor U. Hayn-Leichsenring   +3 more
doaj   +1 more source

CHOSEN: Contrastive Hypothesis Selection for Multiview Depth Refinement

Proceedings of the Conference on Robots and Vision
We propose CHOSEN, a simple yet flexible, robust and effective multi-view depth refinement framework. It can be employed in any existing multi-view stereo pipeline, with straightforward generalization capability for different multi-view capture systems such as camera relative positioning and lenses. Given an initial depth estimation, CHOSEN iteratively
Di Qiu, Yinda Zhang 0001, Thabo Beeler, Vladimir Tankovich, Christian Häne, Sean Fanello, Christoph Rhemann, Sergio Orts-Escolano   +7 more
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source