Results 61 to 70 of about 7,979,651 (342)

Electroretinography and contrast sensitivity, complementary translational biomarkers of sensory deficits in the visual system of individuals with Fragile X Syndrome [PDF]

, 2021
Olivier Perche, Fabien Lesne, Alain Patat, Susanne Raab, Roy E. Twyman, Robert H. Ring, Sylvain Briault   +6 more
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Development of Dynamic Contrast Sensitivity Chart

British and Irish Orthoptic Journal
Background: Dynamic visual acuity (DVA) is a complex visual function that requires the observer to detect a moving target, to visually acquire it by eye movements, and to resolve critical details contained in it, in a relatively brief time exposure ...
Nikhita Jacob, Vandana Kamath, B. N. Sanjay   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Contrast-enhanced optical coherence tomography with picomolar sensitivity for functional in vivo imaging

Scientific Reports, 2016
Optical Coherence Tomography (OCT) enables real-time imaging of living tissues at cell-scale resolution over millimeters in three dimensions. Despite these advantages, functional biological studies with OCT have been limited by a lack of exogenous ...
O. Liba, E. SoRelle, Debasish Sen, A. de la Zerda   +3 more
semanticscholar   +1 more source

The Measurement of Contrast Sensitivity in Near Vision: The Use of a Digital System vs. a Conventional Printed Test

Technologies
In recent years, there has been intense development of digital diagnostic tests for vision. All of these tests must be validated for clinical use.
Kevin J. Mena-Guevara, David P. Piñero, María José Luque, Dolores de Fez   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Evaluation of contrast sensitivity in visually impaired individuals using K-CS test. A novel smartphone-based contrast sensitivity test-Design and validation.

PLoS ONE
BackgroundTo describe the development and investigate the accuracy of a novel smartphone-based Contrast Sensitivity (CS) application, the K-CS test.MethodsA total of 67 visually impaired and 50 normal participants were examined monocularly using the ...
Vasileios Karampatakis, Eleni P Papadopoulou, Stavroula Almpanidou, Leonidas Karamitopoulos, Diamantis Almaliotis   +4 more
doaj   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Temporal Expectation Enhances Contrast Sensitivity by Phase Entrainment of Low-Frequency Oscillations in Visual Cortex

Journal of Neuroscience, 2013
Although it is increasingly accepted that temporal expectation can modulate early perceptual processing, the underlying neural computations remain unknown.
A. Cravo, G. Rohenkohl, V. Wyart, A. Nobre   +3 more
semanticscholar   +1 more source