Results 71 to 80 of about 7,979,651 (342)

Sensitivity to Auditory Velocity Contrast [PDF]

open access: yesScientific Reports, 2016
AbstractA natural auditory scene often contains sound moving at varying velocities. Using a velocity contrast paradigm, we compared sensitivity to velocity changes between continuous and discontinuous trajectories. Subjects compared the velocities of two stimulus intervals that moved along a single trajectory, with and without a 1 second inter stimulus
Shannon M. Locke   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluation of Color Contrast Sensitivity in Dyslexic Children

open access: yesمجله پژوهش در علوم توانبخشی, 2014
Introduction: Although there is a consensus about the importance of vision perception in reading, its role in development of dyslexia is highly debated. In order to understand the relationship between dyslexia and disorders of visual perception, we have ...
Alireza Mohamadi, Ebrahim Jafarzadehpur
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Contrast sensitivity, healthy aging and noise.

open access: yesVision Research, 2013
At least three studies have used external noise paradigms to investigate the cause of contrast sensitivity losses due to healthy aging. These studies have used noise that was spatiotemporally localized on the target.
R. Allard   +3 more
semanticscholar   +1 more source

The importance of contrast sensitivity testing in children

open access: yesBritish and Irish Orthoptic Journal, 2014
Aim:  To discuss the information contrast sensitivity (CS) testing can provide over visual acuity testing, and review the literature relating to CS deficits in children to determine whether there is an optimum test available.
Ashli F. Milling   +2 more
doaj   +1 more source

A comparative study of fibrin glue versus suturing on contrast sensitivity in patients undergoing pterygium excision with free conjunctival autograft [PDF]

open access: green, 2022
Mohammad Khalilzad   +6 more
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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