Results 101 to 110 of about 12,459,419 (300)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Contrastive Topics in Pairing Answers: A Cross-Linguistic Production Study [PDF]

, 2007
Skopeteas S, Féry C. Contrastive Topics in Pairing Answers: A Cross-Linguistic Production Study. In: Featherston S, Sternefeld W, eds. Linguistic Evidence 2006.
Sternefeld, Wolfgang, Féry, Caroline, Featherston, Sam, Skopeteas, Stavros   +3 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Perspective (Institute for Christian Studies)

, 2015
The laudatio for Dianne Bergsma by James Olthuis appeared in Perspective 48, no. 2 (Sept 2014) http://hdl.handle.net/10756/332755Master of Worldview Studies: To New York and Beyond -- Student Achievements -- Enhancing Global Access to ICS Research ...
Guthrie-McNaughton, Isabella, Hoff, Shannon, Ansell, Nicholas, Institute for Christian Studies, Blomberg, Doug, Sweetman, Robert, Kuipers, Ronald A., Strauss, Gideon, Witvoet, Bert   +8 more
core   +1 more source

A research agenda for contrastive analysis of Japanese and Kazakh: The case of grammar and pragmatics

Әл-Фараби Атындағы Қазақ Ұлттық Университеті хабаршы шығыстану сериясы, 2016
This paper aims at conducting studies on contrastive linguistics of Japanese and Kazakh and interlanguage studies of Kazakh learners’ Japanese.  The paper indicates research themes of contrastive analysis of the languages from the view point of grammar (
Т Ниномия, А Бекебасова   +1 more
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Contrastive analysis of reformulation markers in English and Italian

, 2013
The aim of this paper is a contrastive analysis of reformulation markers in spoken English and Italian. Broadly speaking, reformulation markers are a particular kind of discourse markers that allow the speaker to revisit a previous statement (Gülich ...
International Contrastive Linguistics Conference VII & Using Corpora in Contrastive and Translation Studies III, Ciabarri, Federica   +1 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

On a Contrastive Criterion of Testability II: The Material Inadequacy of Contrastive Testability [PDF]

, 2011
Elliott Sober has suggested his contrastive criterion of testability as an improvement over previous criteria of empirical significance like falsifiability and the standard Bayesian criterion of empirical significance.
Lutz, Sebastian
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source