Results 121 to 130 of about 12,459,419 (300)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Corpus-based Approaches to Contrastive Linguistics and Translation Studies
Corpus-based Approaches to Contrastive Linguistics and Translation Studies presents readers with up-to-date research in corpus-based contrastive linguistics and translation studies, showing the high degree of complementarity between the two fields in ...
Lerot, Jacques +2 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Corpus-based Approaches to Contrastive Linguistics and Translation Studies
Corpus-based Approaches to Contrastive Linguistics and Translation Studies presents readers with up-to-date research in corpus-based contrastive linguistics and translation studies, showing the high degree of complementarity between the two fields in ...
Lerot, Jacques +2 more
core
Unsupervised Bilingual POS Tagging with Markov Random Fields [PDF]
In this paper, we give a treatment to the problem of bilingual part-of-speech induction with parallel data. We demonstrate that naive optimizationof log-likelihood with joint MRFs suffers from a severe problem of local maxima,and suggest an alternative –
Chen, Desai +3 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A contrastive learning approach for time series with application to anomaly detection in healthcare [PDF]
openTime-series analysis, particularly in biomedical signals like Electrocardiograms (ECG), poses the critical challenge of distinguishing between global patterns shared across subjects and individual-specific features unique to each patient.
KOLICI, GRISELDA
core
1 online resource (PDF, page 392-410)Sober, Elliott. (1990). Contrastive empiricism.
Sober, Elliott
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