Results 171 to 180 of about 17,739,623 (305)

Evaluating substance use outcomes of recreational cannabis legalization using a unique co-twin control design. [PDF]

Am J Drug Alcohol Abuse, 2023
Ross JM, Karoly HC, Zellers SM, Ellingson JM, Corley RP, Iacono WG, Hewitt JK, McGue M, Vrieze S, Hopfer CJ.   +9 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Electric Eel foraging optimization based control design of islanded microgrid. [PDF]

Sci Rep
Ebrahim MA, Ragab AS, Aziz BA, AbdelHadi HA.   +3 more
europepmc   +1 more source

Testing a Culturally Tailored Advance Care Planning Intervention (MY WAY) for an American Indian Tribe: Protocol for a Quasi-Experimental Waitlist Control Design. [PDF]

JMIR Res Protoc, 2023
Anderson E, Goins RT, Haozous EA, Schweinhart A.   +3 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Intelligent Robust Control Design with Closed-Loop Voltage Sensing for UPS Inverters in IoT Devices. [PDF]

Sensors (Basel)
Chang EC, Tseng YW, Cheng CA.
europepmc   +1 more source

Moisture control design has to respond to all relevant hygrothermal loads. [PDF]

UCL Open Environ, 2022
Künzel H, Dewsbury M.
europepmc   +1 more source

Traffic control signal design manual

, 2009
Title from PDF cover (DOT web site, viewed Dec. 3, 2009).; Previously published: Manual of traffic control signal design. [Wethersfield, Conn] : Dept. of Transportation, Bureau of Highways, Office of Engineering, Division of Traffic, [1984].; Includes ...

core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Output Feedback Integrated Guidance and Control Design for Autonomous Underwater Vehicles Against Maneuvering Targets. [PDF]

Sensors (Basel)
Wang R, Lu J, Lyu S, Liu Y, Cui Y.
europepmc   +1 more source