Results 201 to 210 of about 17,739,623 (305)

Robust Optimal Control Design for Performance Enhancement of PWM Voltage Source Inverter. [PDF]

Micromachines (Basel), 2022
Chang EC, Cheng HL, Chang CH, Wu RC, Cheng CA, Xiao ZK, Lu WJ, Wei ZY.   +7 more
europepmc   +1 more source

1140.09 Shoulders 1140.10 Medians Full Design Level 1140.11 Curbs 1140.12 Parking 1140.13 Pavement Type 1140.14 Structure Width 1140.15 Right of Way Width 1140.16 Grades 1140.17 Fencing

Full design level is the highest level of design and is used on new and reconstructed highways. These projects are designed to provide optimum mobility, safety, and efficiency of traffic movement.
Design Speed, Traffic Signal Control
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Research on optimal control design of displaced left turn signal at one two way and three one way traffic intersections. [PDF]

Sci Rep
Han N, Cheng G, Lin J, Tang Z, Xie F.
europepmc   +1 more source

Outcomes of kidney transplantation in patients with congenital anomalies of the kidney and urinary tract: a propensity-score-matched analysis with case-control design. [PDF]

Turk J Med Sci, 2023
Oto ÖA, Mirioğlu Ş, Yazıcı H, Dirim AB, Güller N, Şafak S, Demir E, Artan AS, Özlük MY, Türkmen A, Çalışkan YK, Lentine KL.   +11 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Effect of nursing intervention based on Ratu's model for preventing postpartum blues and depression among primiparous women: A treatment-control design. [PDF]

Womens Health (Lond)
Mohamed AH, Abobaker RM, Ibrahim MIT, AlHseinat MM, Ali HM, Razek RAA, Albougami A, Berdida DJE, Elrefaey SRI.   +8 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Cascade Proportional-Integral Control Design and Affordable Instrumentation System for Enhanced Performance of Electrolytic Dry Cells. [PDF]

Sensors (Basel)
Matos SN, Reis GPD, Leal EM, Figueiredo RL, Euzébio TAM, Rêgo Segundo AK.   +5 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source