Results 141 to 150 of about 7,679,447 (385)
Requirements Engineering for Control Systems
, 2009 Nowadays, more and more controllers in automobiles are realised in software on electronic control units. This contribution reports on a joined project of control system engineers and software engineers that aims at a better integration of these two disciplines. Focussing the requirements engineering part, the relevant issues for control systems are set
openaire +3 more sources
, 1997 At a time when many companies are under pressure to reduce "times-to-market" the management of product information from the early stages of design through assembly to manufacture and production has become increasingly important.
Baker, N. +12 more
core +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering
Journal of the Royal Society Interface, 2016 Fei He, Ettore Murabito, H. Westerhoff
semanticscholar +1 more source
The role of the host in a cooperating mainframe and workstation environment, volumes 1 and 2 [PDF]
In recent years, advancements made in computer systems have prompted a move from centralized computing based on timesharing a large mainframe computer to distributed computing based on a connected set of engineering workstations.
Kusmanoff, Antone, Martin, Nancy L.
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Reliability Analysis of Complex NASA Systems with Model-Based Engineering [PDF]
The emergence of model-based engineering, with Model- Based Systems Engineering (MBSE) leading the way, is transforming design and analysis methodologies.
Alimardani, Mahdi +2 more
core +1 more source