Results 81 to 90 of about 703,458 (267)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Nussbaum functions in adaptive control with time-varying unknown control coefficients

open access: yesAutomatica, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Determination of nutrient and energy values of cottonseed meal supplemented or not with phytase and protease for broiler chicks

open access: yesRevista Brasileira de Zootecnia
The objective of this study was to determine the nutritional and energy compositions of cottonseed meal (CM), with or without enzyme supplementation, for broilers at different ages.
Alcilene Maria Andrade Tavares-Samay   +5 more
doaj   +1 more source

Coupling coefficient in antiguided coupling: magnitude and sign control

open access: yesJournal of the Optical Society of America B, 2018
The coupling coefficient between two passive antiguided waveguides is investigated. A novel approach for identifying the in-phase and out-of-phase coupled modes in an antiguided system through the dispersion curves is described. The coupling coefficient in these modes is found to be real, and its sign and magnitude are influenced by the thickness and ...
Zihe Gao   +2 more
openaire   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

On the optimal coefficient control in a heat equation

open access: yesDiscrete and Continuous Dynamical Systems - S, 2018
In this study, optimal control of a senior coefficient in a heat conduction problem is discussed. Since such problems are severely ill-posed, it is necessary to regularize them. So, we present the regularization process which has a great importance for a optimal control problem in this study.
Seda İǧret Araz, Murat Subașı
openaire   +1 more source

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