Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
[Unequal impact of COVID-19 on mortality in long-term care homes across health areas of Castilla-La Mancha (Spain)]. [PDF]
Zunzunegui Pastor MV +3 more
europepmc +1 more source
Control de procesos multivariables no lineales empleando lógica difusa
Los procesos involucrados en ramas como la Ingeniería Química resultan ser de naturaleza no lineal; algunos de ellos, como los procesos de destilación, presentan fuertes no linealidades y acoplamiento entre variables de proceso. Típicamente, las técnicas convencionales de control usadas en este tipo de equipo tienen involucrados controladores del tipo ...
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Revealing the past of Ginah archaeological site by enhancing GPR images to understand ancient periods at Kharga Oasis, Egypt. [PDF]
Ebraheem MO, Ibrahim HA, Zalat MM.
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
The Insecticide Imidacloprid Promotes Algal Growth in Absence of Zooplankton. [PDF]
Lozano VL +2 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
[Linear power and mortality in COVID-19 respiratory difficulty syndrome]. [PDF]
Lizama-Aguilar A +4 more
europepmc +1 more source

