Results 111 to 120 of about 6,425,712 (293)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Stability Analysis of DC Microgrids: Insights for Enhancing Renewable Energy Integration, Efficiency and Power Quality

open access: yesApplied Sciences
In the current context of smart grids, microgrids have proven to be an effective solution to meet the energy needs of neighborhoods and collective buildings.
António Sousa   +2 more
doaj   +1 more source

Leishmaniasis and textbook: how are endemic diseases addressed in public education? [PDF]

open access: yesInvestigações em Ensino de Ciências, 2014
Visceral Leishmaniasis is a vector-borne zoonosis, considered a public health problem in Brazil, because of their magnitude, geographic expansion and lethality. The disease is the etiologic agent trypanosamatid Leishmania infantum, is transmitted by the
Débora Batista Reis   +2 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Control Strategies

open access: yes, 2015
This chapter studies control strategies. Control strategies are listed and explained. It focuses on modeling vaccination in single-strain and multistrain diseases. Different modes of introducing vaccination in models are shown. Imperfect vaccination as a mechanism leading to backward bifurcation and strain replacement is explained.
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Are cause of death data for Shanghai fit for purpose? A retrospective study of medical records

open access: yesBMJ Open, 2022
Jun Chen   +20 more
doaj   +1 more source

Overview of increasing the penetration of renewable energy sources in the distribution grid by developing control strategies and using ancillary services [PDF]

open access: yes, 2014
Increasing the renewables energy resources in the distribution network is one of the main challenges of the distributed system operator due to instability, power quality and feeder capacity problems. This paper proposes a solution for further penetration
Bozalakov, Dimitar   +3 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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