Results 101 to 110 of about 28,036,800 (305)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Non-parametric H-infinity control synthesis with suboptimal controller sets
, 2008 The effectiveness of norm-based control methodologies heavily relies on the quality of the model that describes the dynamic behavior of the plant. In practical applications, the requirement to accurately describe the system at hand often results in high ...
Steinbuch, M Maarten +9 more
core
An algorithm for weak synthesis observation equivalence for compositional supervisor synthesis [PDF]
, 2012 This paper proposes an algorithm to simplify automata in such a way that compositional synthesis results are preserved in every possible context. It relaxes some requirements of synthesis observation equivalence from previous work, so that better ...
Fabian, Martin, +4 more
core +1 more source
The Journal of Engineering, 2019 Providing additional damping for system electromechanical oscillations through doubly fed induction generator (DFIG)-based wind turbines is investigated in this study.
Mohammad Jafarian, Mohammad-Naser Asefi
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2015 This paper addresses the L2-gain analysis and control synthesis problem for a class of switched nonlinear systems affected by both time-varying uncertainties and external disturbances.
Dimirovski, Georgi, Zhao, Jun, Wang, Min
core +1 more source
IET Cyber-systems and Robotics, 2019 This study presents a combination of the robust passivity-based controller (RPBC) and an extended state observer (ESO) for the tracking control of a three degree-of-freedom PUMA 500 robot manipulator under parameter variations and external disturbances ...
Mohammed Ali +2 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source