Results 81 to 90 of about 5,938,459 (354)

MODAL SYNTHESIS OF CONTROL ALGORITHMS FOR MULTIDIMENSIONAL SYSTEMS WITH A GIVEN SPECTRUM WITH INCOMPLETE INFORMATION

, 2023
O.H. Boeva, Ch.Q. Ibragimova
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Modifying the control design of DFIG-based wind turbines in order to inhibit power system oscillations

The Journal of Engineering, 2019
Providing additional damping for system electromechanical oscillations through doubly fed induction generator (DFIG)-based wind turbines is investigated in this study.
Mohammad Jafarian, Mohammad-Naser Asefi
doaj   +1 more source

Synthesis and modeling of automatic control system of shredded aggregate based on fuzzy logic

, 2022
Ivan Marynych, Oleksandra Serdiuk
openalex   +1 more source

Language-Guided Controller Synthesis for Linear Systems

IEEE Transactions on Automatic Control, 2014
This paper considers the problem of controlling discrete-time linear systems from specifications given as formulas of syntactically co-safe linear temporal logic over linear predicates in the state variables. A systematic procedure is developed for the automatic computation of sets of initial states and feedback controllers such that all the resulting ...
Aydin Gol, E. (Ebru), Lazar, M., Belta, C.   +2 more
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Robust tracking control of a robot manipulator using a passivity-based extended-state observer approach

IET Cyber-systems and Robotics, 2019
This study presents a combination of the robust passivity-based controller (RPBC) and an extended state observer (ESO) for the tracking control of a three degree-of-freedom PUMA 500 robot manipulator under parameter variations and external disturbances ...
Mohammed Ali, C.K. Alexander, C.K. Alexander   +2 more
doaj   +1 more source

Partial derivatives of the Vandermonde determinant and their application to the synthesis of linear control systems [PDF]

, 1973
Tadeusz Kaczorek, Tadeusz Traczyk
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source