Results 51 to 60 of about 286,683 (311)

Faire bifurquer le tourisme hivernal ? Controverses et mobilisations socio-environnementales autour de la transition écologique dans une station alpine (La Clusaz, France)

open access: yesMondes du Tourisme
Based on the case of the project to create a high-altitude reservoir at La Clusaz ski resort in France, this article analyses the opposing appropriations of the so-called ecological transition in the mountains.
Mikaël Chambru, Marion Picard
doaj   +1 more source

Advances in Psychiatric Diagnosis: Past, Present, and Future

open access: yesBehavioral Sciences, 2017
This editorial examines controversies identified by the articles in this special issue, which explore psychopathology in the broad history of the classification of selected psychiatric disorders and syndromes over time through current American criteria ...
Carol S. North, Alina M. Surís
doaj   +1 more source

Political ecology of Bruno Latour [PDF]

open access: yesFilozofija i Društvo, 2012
The paper explores Latour’s conception of political ecology and its theoretical and political implications. The first part of the paper shows Latour’s critique of theoretical frameworks of scientific and political practices, which, in his opinion ...
Birešev Ana
doaj   +1 more source

The Blood Microbiome and Health: Current Evidence, Controversies, and Challenges [PDF]

open access: gold, 2023
Hong Sheng Cheng   +5 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Controversia y discurso histórico en la temprana Edad Moderna

open access: yesCriticón, 2019
This article surveys the theoretical discourse about the forms and uses of controversy in early modern Spanish historiography. This discourse is examined in the light of the rise of history as a useful resource for polemics.
Cesc Esteve
doaj   +1 more source

Les régimes de rationalité en environnement à travers le prisme des valeurs

open access: yesArgumentation et Analyse du Discours, 2020
Whereas social acceptability is emerging as a decisive criterion for evaluating the impact of infrastructure projects, this article examines the ways in which regimes of ethical rationalities can be mobilized in an environmental issue surrounding the ...
Olivier Turbide, Thomas Maxwell
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

„Orlové literární revoluce.“ F. X. Šalda a/versus Arnošt Procházka (a Moderní revue) || ‘The Eagles of Literary Revolution’: F. X. Šalda and / versus Arnošt Procházka (and Moderní Revue) [PDF]

open access: yesSlovo a Smysl, 2018
The development of a professional network, as well as long-standing disputes, among the most prominent representatives of Czech modernism at the turn of the 19th and 20th centuries — F. X.
Luboš Merhaut
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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