Results 61 to 70 of about 286,683 (311)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Les médecins aux bords de leurs savoirs
Revue d'anthropologie des connaissances, 2016 When doctors operate on the margins of their jurisdiction and are faced with challenges that do not fall strictly within the pathological framework, they are called to deal with situations that medical knowledge cannot always adequately address ...
Thomas Bujon, Christine Dourlens
doaj +1 more source
A narrative review of the social determinants of lung cancer screening: knowledge gaps and controversies [PDF]
, 2023 Sakib M. Adnan +3 more
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Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Fracturing Debate? A Review of Research on Media Coverage of “Fracking”
Frontiers in Communication, 2018 Hydraulic fracturing is an energy extraction process that is increasingly attracting controversy. This article seeks to outline how the media report hydraulic fracturing (or “fracking”), and to explore its place within the reporting of energy concerns ...
Julian Matthews, Anders Hansen
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FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Rhetoric and dialetics, the tribute of journalism to the Greco-Roman [PDF]
Estudos em Comunicação, 2011 The article draws on the concepts of rhetoric and dialectic, questioning their relationship with journalism, seeking to understand what is the contribute of dialectics to journalism.
Vanessa Hauser +1 more
doaj
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
The Journal of Experimental Medicine, 2006 How do neutrophils kill pathogens? A 1967 paper by Seymour Klebanoff provided a neat answer. But far from being resolved, the question still provokes vehement arguments.
openaire +2 more sources