Results 81 to 90 of about 442,501 (289)
Revue de la Régulation, 2015 This thesis explores the analytical scope offered by the notion of performativity of economics. After having emphasize that its principal limit was its difficulty of provide a clear theorization of potential failures of performativity, we set a new ...
Nicolas Brisset
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Revue de la Régulation, 2015 Health care financing in Europe has become more private because of the retrenchment of public health insurance, the increased reliance on private insurance, greater cost-sharing and household out-of-pocket payments.
Philippe Batifoulier
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Développement Durable et Territoires, 2017 Public authorities in charge of preparing and implementing the 1964 French water law and the 2000 European Water framework Directive similarly relied on inventories. In order to justify public action, they needed to objectify a situation which was either
Gabrielle Bouleau +3 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Are Natural Languages Necessary?
Crítica, 2019 Against Davidson's criticism of the usual notion of a natural language, Dummett and most philosophers of language have argued that such a notion is necessary to account for the normativity of meaning and to avoid declaring meaningless much of our ...
Manuel Hernández Iglesias
doaj +1 more source
Conventional Mechanical Ventilation
Saudi Journal of Anaesthesia, 2010 The provision of mechanical ventilation for the support of infants and children with respiratory failure or insufficiency is one of the most common techniques that are performed in the Pediatric Intensive Care Unit (PICU). Despite its widespread application in the PICUs of the 21st century, before the 1930s, respiratory failure was uniformly fatal due ...
openaire +3 more sources