Results 111 to 120 of about 4,182,360 (301)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Journal of the Dow University of Health Sciences, 2010 Introduction: Exponential growth ofknowledge in the biomedical field has forced the medical educatorsfor a change from traditional to integrated curriculum and conventional assessment techniques to newerstructured techniques.
Anila Jaleel, Noreen Jaffrey
doaj
A COMPARISON OF SUSTAINABLE AND CONVENTIONAL FARMERS IN NORTH DAKOTA [PDF]
Interviews and mail-out/mail-back surveys were conducted in 1992 with 38 conventional and 41 sustainable North Dakota farmers. The results emphasize the differences and similarities of these two types of farmers.
Youngs, George A., Jr. +3 more
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Applied SciencesIn this study, Italian and French wines produced through organic and conventional methods were analyzed. Three different varieties of wines were examined, including Cabernet Sauvignon, Merlot, and Syrah.
Alicja Ponder +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Phytate Content in Cereals Impacted by Cropping System and Harvest Year
FoodsPhytate is a substance that has been considered mainly as an antinutrient, but at the same time it is a significant source of phosphorus and has several useful health-related properties that could be exploited.
Mailiis Korge +7 more
doaj +1 more source