Results 121 to 130 of about 6,639,178 (282)
Ganda Wibowo,1,2 Dyah Wulan Anggrahini,1,2 Rochmi Isnaini Rismawanti,1 Vita Arfiana Nurul Fatimah,1 Alhadi Hakim,1 Rachmadya Nur Hidayah,3 Putrika Prastuti Ratna Gharini1,2 1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public ...
Wibowo G +6 more
doaj
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Conventional and unconventional monetary policy [PDF]
The authors extend a standard New Keynesian model to incorporate heterogeneity in spending opportunities and two sources of (potentially time-varying) credit spreads and to allow a role for the central bank's balance sheet in equilibrium determination ...
Michael Woodford, Vasco Cúrdia
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Introduction: Exponential growth ofknowledge in the biomedical field has forced the medical educatorsfor a change from traditional to integrated curriculum and conventional assessment techniques to newerstructured techniques.
Anila Jaleel, Noreen Jaffrey
doaj
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
In this study, Italian and French wines produced through organic and conventional methods were analyzed. Three different varieties of wines were examined, including Cabernet Sauvignon, Merlot, and Syrah.
Alicja Ponder +3 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Phytate Content in Cereals Impacted by Cropping System and Harvest Year
Phytate is a substance that has been considered mainly as an antinutrient, but at the same time it is a significant source of phosphorus and has several useful health-related properties that could be exploited.
Mailiis Korge +7 more
doaj +1 more source
Conventional Necessity and the Contingency of Convention
I defend a conventionalist view of logical and (some) mathematical truths against the criticisms of Quine and Stroud. Conventionalism is best formulated by appealing to sense-conferring rules governing important logical and mathematical expressions. Conventional necessity can be understood as arising from these rules in a way that is immune to Quine's ...
openaire +1 more source

