Results 61 to 70 of about 386,320 (315)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Convergence Properties of an Extended Least Squares (ELS) Variant [PDF]

open access: yesModeling, Identification and Control, 2000
By factorizing the A- and B-polynomials in an ARMAX model and filtering the input/output data with the appropriate factors thereof, the parameters of the model can be estimated in a decentralized fashion.
Rolf Henriksen
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Habitual Cross-legged Sitting Increases Lumbopelvic Rotation Asymmetry

open access: yesPhysical Therapy Korea
Background: Cross-legged sitting posture (CLSP) is common in daily life but may cause asymmetrical loading of the pelvis and spine, potentially leading to postural imbalance and musculoskeletal problems.
Han Seung-yoon   +4 more
doaj   +1 more source

Finite Element Analysis and Electrohydrodynamic Multiphysics Modeling of a Corona-Streamer Discharge in a Two-Phase Flow Medium

open access: yesEnergies
This study proposes an electrohydrodynamic multiphysics modeling and finite element analysis technique to accurately simulate corona-streamer discharges in a two-phase flow medium.
Myung-Ki Baek, Ho-Young Lee
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Local Convergence Analysis of FastICA

open access: yes, 2006
The FastICA algorithm can be considered as a selfmap on a manifold. It turns out that FastICA is a scalar shifted version of an algorithm recently proposed. We put these algorithms into a dynamical system framework. The local convergence properties are investigated subject to an ideal ICA model.
Hao Shen 0002, Knut Hüper
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Convergence analysis of online algorithms [PDF]

open access: yesAdvances in Computational Mathematics, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Real convergence in Europe: A cluster analysis [PDF]

open access: yesEconomic Modelling, 2013
In this paper we analyse real convergence in GDP per worker in the EU member states. The aim is to test whether there is evidence of club convergence in the EU, i.e. divergence in GDP per worker. Evidence in favour of cluster or club convergence may be an indication of significant productivity divergences between countries, which may also explain the ...
Juan Carlos Cuestas   +2 more
openaire   +4 more sources

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