Results 71 to 80 of about 228,280 (310)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On spherical averages of radial basis functions
, 2008 A radial basis function (RBF) has the general form $$s(x)=\sum_{k=1}^{n}a_{k}\phi(x-b_{k}),\quad x\in\mathbb{R}^{d},$$ where the coefficients a 1,…,a n are real numbers, the points, or centres, b 1,…,b n lie in ℝ d , and φ:ℝ d →ℝ is a radially symmetric
Baxter, Brad J.C.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
On Properties of the Choquet Integral of Interval-Valued Functions
Journal of Applied Mathematics, 2011 Based on the concept of an interval-valued function which is motivated by the goal to represent an uncertain function, we define the Choquet integral with respect to a fuzzy measure of interval-valued functions.
Lee-Chae Jang
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Fourier transforms of Lipschitz functions on the hyperbolic plane H2
International Journal of Mathematics and Mathematical Sciences, 1998 The purpose of the present work is to study the order of magnitude of the Fourier transforms fˆ(λ) for large λ of complex-valued functions f(z) sating certain Lipschitz conditions in the non-Euclidean hyperbolic plane H2.
M. S. Younis
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Autocontinuity and convergence theorems for the Choquet integral [PDF]
Our aim is to provide some convergence theorems for the Choquet integral with respect to various notions of convergence. For instance, the dominated convergence theorem for almost uniform convergence is related to autocontinuous set functions ...
Yann Rébillé
core
Some Topological Properties of The Set of Filter Cluster Functions
Kuwait Journal of Science, 2016 In [1], we generalized the concepts of pointwise convergence, uniform convergence and alpha-convergence for sequences of functions on metric spaces by using the filters on N. Then, in [2], we defined the concepts of limit function, F-limit function and F-
Huseyin Albayrak +2 more
doaj