Results 81 to 90 of about 228,280 (310)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Space of quasicontinuous functions with the topology of uniform convergence on semi-compacta

open access: yesApplied General Topology
We introduce a new set-open topology on function spaces namely the semi-compact-open topology. The topology of uniform convergence on semi-compacta lies between the topology of pointwise convergence and the topology of uniform convergence.
Neelim Kumar Barman, Debajit Hazarika
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Uniform convergence and pointwise convergence

open access: yes, 2010
The aim of this material is to introduce the student to two notions of convergence for sequences of real-valued functions. The notion of pointwise convergence is relatively straightforward, but the notion of uniform convergence is more subtle.
Feinstein Joel F. Dr
core  

The convergence classes of Collatz function

open access: yesTheoretical Computer Science, 2011
AbstractThe Collatz conjecture, also known as the 3x+1 conjecture, can be stated in terms of the reduced Collatz function R(x)=(3x+1)/2h (where 2h is the larger power of 2 that divides 3x+1). The conjecture is: Starting from any odd positive integer and repeating R(x) we eventually get to 1.
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A rate of convergence in clustering analysis. [PDF]

open access: yes
We present a result about stochastic boundedness of stable empirical processes on Vapnik-Cervonenkis classes of functions and we apply it to obtain a rate of convergence for the approximation between the sample and the populational variation in the k ...
Romo, Juan
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Lacunary strong convergence with respect to a sequence of modulus functions [PDF]

open access: yes, 1995
summary:The definition of lacunary strong convergence is extended to a definition of lacunary strong convergence with respect to a sequence of modulus functions in a Banach space.
Fisher, Brian, Pehlivan, Serpil
core  

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