Results 31 to 40 of about 63,676 (305)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

CONVERGENCE OF PROBABILITY MEASURES REVISITED * [PDF]

open access: yes, 2005
. The hypo-convergence of upper semicontinuous functions provides a natural framework for the study of the convergence of probability measures.
Gabriella Salinetti
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Conflict Management for Target Recognition Based on PPT Entropy and Entropy Distance

open access: yesEnergies, 2021
Conflicting evidence affects the final target recognition results. Thus, managing conflicting evidence efficiently can help to improve the belief degree of the true target.
Shijun Xu   +5 more
doaj   +1 more source

Weak Convergence of Probability Measures

open access: yes, 2020
Lecture notes based on the book Convergence of Probability Measures by Patrick Billingsley.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A Discrete Limit Theorem for L-Functions of Elliptic Curves

open access: yesJaunųjų Mokslininkų Darbai, 2018
In the paper, we prove the discrete limit theorem in the sense of the weak convergence of probability measures in the space of analytic on DV = {s ∈ C : 1 < σ < 3/2, |t|  0 be a fixed real number such that exp {2πk/h} is an irrational number for all k∈Z\{
Virginija Garbaliauskienė   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

On Value Distribution of Certain Beurling Zeta-Functions

open access: yesMathematics
In this paper, the approximation of analytic functions by shifts ζP(s+iτ) of Beurling zeta-functions ζP(s) of certain systems P of generalized prime numbers is discussed. It is required that the system of generalized integers NP generated by P satisfies ∑
Antanas Laurinčikas
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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