Results 41 to 50 of about 228,817 (308)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Extended convergence of two-step iterative methods for solving equations with applications
Journal of Numerical Analysis and Approximation TheoryThe convergence of two-step iterative methods of third and fourth order of convergence are studied under weaker hypotheses than in earlier works using our new idea of the restricted convergence region.
Ioannis K. Argyros, Santhosh George
doaj +1 more source
Processy konvergencii i divergencii v regionah Evropejskogo sojuza: osobennosti i kvalimetrija [Processes of convergence and divergence in the re-gions of the European Union: features and qualimetry] [PDF]
Балтийский регион, 2013 A higher level of unity and cohesion across the European Union member states is an important aspect of European integration though it has a rather ambiguous nature.
Voronov Viktor, Lavrinenko Olga
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Geophysical Research Letters, 2019 Understanding the variations in the strength of Madden‐Julian Oscillation (MJO) events as they propagate across the Indo‐Pacific Maritime Continent has been an unmet challenge.
Samson Hagos +4 more
doaj +1 more source
Processes of convergence and divergence in the regions of the European Union: features and qualimetry [PDF]
Baltic Region, 2013 A higher level of unity and cohesion across the European Union member states is an important aspect of European integration though it has a rather ambiguous nature.
Voronov Viktor, Lavrinenko Olga
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Decentralization, Social Capital and Regional Convergence [PDF]
SSRN Electronic Journal, 2013 By studying the interaction between social capital and decentralization, we show that political decentralization can be a source of divergence across heterogeneous regions. In particular, we claim that since the local endowments of social capital display their effect on the economy mainly through the functioning of local institutions, decentralization ...
Mauro L, PIGLIARU, FRANCESCO
openaire +5 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source