Results 71 to 80 of about 224,580 (266)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Spatiotemporal evolution pattern and convergence of healthy city development in China
International Journal of Health GeographicsBackground Urbanization-induced urban diseases threaten public health. The World Health Organization launched the Healthy City Initiative in 1986, and China has incorporated it into the Healthy China 2030 strategy.
Fulei Jin, Yanli Geng, Xigang Zhang
doaj +1 more source
BUCHAREST-ILFOV REGION – BETWEEN ECONOMIC AND SOCIAL CONVERGENCE AND DIVERGENCE [PDF]
CES Working Papers, 2014 This paper aims to highlight the main economic disparities between the developing regions of Romania, during the 2005-2011/2012 period. We will focus on the Bucharest-Ilfov region, which differs both in terms of population density, and the galloping ...
Catalina Mihaela Badoiu
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Regional Convergence in Brazil
This paper examines whether labor productivity converged across Brazil’s states (“departments”) between 2002 and 2018. The results show strong evidence of unconditional convergence in which states with lower levels of initial labor productivity experienced substantially faster labor productivity growth.
Abreha, Kaleb +2 more
openaire +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
When Flexible Forms Are Asked to Flex Too Much
Journal of Agricultural and Resource Economics, 1994 Taylor series-based flexible forms cannot be interpreted as Taylor series approximations unless all data used in estimation lie in a region of convergence.
Paul J. Driscoll
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Examination of Regional Convergence in the Russian Federation
Экономика и управление, 2019 The issues of socio-economic differentiation, regional convergence, identification of influencing factors, and analysis of their impact on spatial economic development are one of the main topics of interest for regional researchers and are widely ...
Tat’yana I. Bezdenezhnykh +1 more
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