Results 81 to 90 of about 224,580 (266)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

The convergence of subspace trust region methods

open access: yesJournal of Computational and Applied Mathematics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhenjun Shi, Zhiwei Xu 0001
openaire   +1 more source

European Region Types in EU-25 [PDF]

open access: yesThe European Journal of Comparative Economics, 2007
In this paper a categorization of 1,212 European NUTS 3 regions is conducted by means of factor and cluster analysis according to economic structure and spatial characteristics.
Christine M. Aumayr
doaj  

Seasonal variation of atmospheric water circulation in the Antarctic region derived from objective analysis data

open access: yesAntarctic Record, 1997
Precipitable water, total moisture flux and its convergence are calculated based on the 6-year (1986-1991) twice-daily U.S. NMC data to investigate the atmospheric water circulation in the Antarctic region. The precipitable water becomes large in summer,
Koji Yamazaki
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Analysis of Regional Income Convergence in Turkey

open access: yesInternational Journal of Research in Business and Social Science (2147- 4478), 2019
This work investigates convergence among regions of Turkey with neoclassical exogenous growth perspective. According to results, it can be stated that there is a tendency of convergence among the regions of Turkey. However, there is an important crisis (2008 crisis) in the investigation period of this study in which the tendency of convergence ...
openaire   +3 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Evolution patterns of detonation gas under different initiation positions in cylindrical charges

open access: yesMeitan xuebao
Improving the utilization efficiency of explosive energy is a crucial research topic in rock blasting. Detonation gas plays a significant role in borehole blasting, yet there is limited research on the evolution patterns of detonation gas from ...
Meng REN   +5 more
doaj   +1 more source

Factors Influencing Economic Integration in East Asia During 1980-2012 Considering the Role of Japan [PDF]

open access: yesFaslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2015
The spread of high economic growth among East Asian countries in the last three decades resulted in increasing attention regarding these countries’ development models.
Nahid Pour-Rostami
doaj  

Home - About - Disclaimer - Privacy