Results 61 to 70 of about 6,349 (218)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Mixed-Timescale Joint Computational Offloading and Wireless Resource Allocation Strategy in Energy Harvesting Multi-MEC Server Systems

IEEE Access, 2019
As an emerging paradigm enabling mobile devices to leverage additional computation resources from nearby MEC servers (MSs), mobile edge computing (MEC) has drawn great attention from academia to industry.
Yinglei Teng, Kang Cheng, Yong Zhang, Xianbin Wang   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Order compatibility for Cauchy spaces and convergence spaces

International Journal of Mathematics and Mathematical Sciences, 1987
A Cauchy structure and a preorder on the same set are said to be compatible if both arise from the same quasi-uniform convergence structure on X. Howover, there are two natural ways to derive the former structures from the latter, leading to “strong” and
D. C. Kent, Reino Vainio
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Irreducible convergence in $T_0$ spaces

Rocky Mountain Journal of Mathematics, 2020
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhao, Bin, Lu, Jing, Wang, Kaiyun
openaire   +3 more sources

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Some remarks about Mackey convergence

International Journal of Mathematics and Mathematical Sciences, 1995
In this paper, we examine Mackey convergence with respect to K-convergence and bornological (Hausdorff locally convex) spaces. In particular, we prove that: Mackey convergence and local completeness imply property K; there are spaces having K- convergent
Józef Burzyk, Thomas E. Gilsdorf
doaj   +1 more source

Fuzzy Counterparts of Fischer Diagonal Condition in ⊤-Convergence Spaces

Mathematics, 2019
Fischer diagonal condition plays an important role in convergence space since it precisely ensures a convergence space to be a topological space. Generally, Fischer diagonal condition can be represented equivalently both by Kowalsky compression operator ...
Qiu Jin, Lingqiang Li, Jing Jiang
doaj   +1 more source