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Virginia Cooperative Extension Volunteers: Extending Knowledge and Improving Lives Updates
, 2021 This is an informational brochure describing Virginia Cooperative Extension volunteer programs, and screening requirements for potential VCE volunteers ...
Proudfoot, Chad
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OSU Extension 100-year History
The Oregon State University Extension Service engages the people of Oregon with research based knowledge and education that strengthen communities and economies, sustain natural resources, and promote healthy families and individuals. This document gives
Oregon State University. Extension Service
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Virginia Cooperative Extension Volunteer Screening Guidelines
, 2020 Frequently asked questions for Virginia Cooperative Extension volunteers.
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Functional Convergence and Extension in Contact
, 2015 This paper investigates the extension of the progressive aspect in contemporary Pennsylvania Dutch. The scope of convergence in contact varieties is a debated subject in theoretical linguistics; the most recent and promising research finds that convergence in contact is not a simple one-to-one mapping, nor an opportunity for any structural anomaly to ...
Josh Brown, Michael T. Putnam
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Kolmogorov Extension, Martingale Convergence, and Compositionality of Processes [PDF]
Proceedings of the 31st Annual ACM/IEEE Symposium on Logic in Computer Science, 2016 We show that the Kolmogorov extension theorem and the Doob martingale convergence theorem are two aspects of a common generalization, namely a colimit-like construction in a category of Radon spaces and reversible Markov kernels. The construction provides a compositional denotational semantics for lossless iteration in probabilistic programming ...
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source