Results 71 to 80 of about 1,550,224 (281)
A reliable algorithm for higher order boundary value problems
Alexandria Engineering Journal, 2023 In this manuscript, extension of residual power series method (RPSM) is proposed for ordinary differential equations with boundary conditions. The extended algorithm is tested against different boundary value problems (BVPs), and results are compared ...
Mubashir Qayyum +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The enigma of cell intercalation
eLifeGeometric criteria can be used to assess whether cell intercalation is active or passive during the convergent extension of tissue.
Raphaël Clément
doaj +1 more source
PLoS ONE, 2011 During gastrulation, convergent extension (CE) cell movements are regulated through the non-canonical Wnt signaling pathway. Wnt signaling results in downstream activation of Rho GTPases that in turn regulate actin cytoskeleton rearrangements essential ...
Katerina Goudevenou +4 more
doaj +1 more source
A Linear Extension of the Martingale Convergence Theorem
The Annals of Probability, 1973 Let $X_1, X_2, \cdots$ be a sequence of random variables satisfying $E(X_{n + 1}\mid X_n, X_{n - 1}, \cdots, X_1) = a_1 X_n + a_2 X_{n - 1} + \cdots + X_{n - k - 1}, n \geqq k$, where $a_1 + a_2 + \cdots + a_k = 1$. Under certain general conditions, mainly that $\sup_nE|X_n| < \infty$, it is shown that $X_n - Y_n \rightarrow\operatorname{a.s.} 0 ...
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Convergent extension analysis in mouse whole embryo culture. [PDF]
Methods Mol Biol, 2012 Mutations have been identified in a non-canonical Wnt signalling cascade (the planar cell polarity pathway) in several mouse genetic models of severe neural tube defects. In each of these models, neurulation fails to be initiated at the 3-4 somite stage, leading to an almost entirely open neural tube (termed craniorachischisis). Studies in whole embryo
Pryor SE +4 more
europepmc +5 more sources
Experimental investigation of chimney-enhanced natural convection in hexagonal honeycombs
Theoretical and Applied Mechanics Letters, 2014 The natural convective heat transfer performance of an aluminum hexagonal honeycomb acting as a novel heat sink for LED cooling is experimentally investigated.
Xiaohu Yang +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source