Results 131 to 140 of about 22,410,299 (279)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Faut-il institutionnaliser l’ECTQG?
, 2017 Le 20e Colloque Européen de Géographie Théorique et Quantitative s’est tenu à York, du 7 au 11 septembre 2017. Organisé par nos collègues de l’université de Leeds, Michelle Morris, Mark Birkin et Nick Malleson, il a réuni environ 80 participants issus de
Cybergeo Conversation
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Conversation between Wu Rongfu and Wu Decai
, 2018 Conversation between Wu Decai and Wu Rongfu, recalling various Duoxu names (finger, hand, etc.)Equipment: Fostex Fr-2 Beyerdynamic M88 N (cardioid) on the left channel ...
Chirkova, Katia, Wang Dehe
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Coffee & Conversation: Trump 2020
, 2019 A Coffee & Conversation About Trump 2020Boston University Howard Thurman Center for Common ...
Boston University Howard Thurman Center for Common Ground
core +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
IPCC Fifth Assessment Report - Conversation commentary
, 2014 With the release of the IPCC\u27s Climate change 2014: impacts, adaptation and vulnerability this week, many Australian academics have contributed to the debate at The Conversation ...
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source