Results 121 to 130 of about 22,410,299 (279)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
In Conversation with Jonah Conversation Analysis, Literary Criticism and the Book of Jonah
The author analyses the various conversations that occur between the characters in the Jonah narrative and the 'conversation' that occurs between the text and its readers. The study opens with an introduction to the field of conversation analysis, with a
Person, Jr Raymond F. +1 more
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La ville à toute heure : le Mobiliscope
, 2017 C'est un outil de géovisualisation qui donne à voir les rythmes quotidiens des villes en tenant compte des mobilités quotidiennes. Développé dans l’UMR Géographie-cités, Mobiliscope, dont nous avons déjà parlé dans notre dernier édito est librement ...
Cybergeo Conversation
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Les métiers de la ville en débat
, 2018 Atelier participatif (source : Agence Ville ouverte) En France comme ailleurs, délimiter le périmètre des métiers de la ville est une question presque toujours controversée.
Cybergeo Conversation
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Migrations et sélections de populations
, 2019 Le CGET vient de publier le rapport 2018 de son Observatoire des territoires, qui traite des mobilités résidentielles en France, mesurées précisément entre 1968 et 2014.
Cybergeo Conversation
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What are we doing when we analyse conversation? [PDF]
, 2008 Here I offer a reminder of some of the phenomenological and ethnomethodological roots of conversation analysis (CA) in the form of a set of 'field propositions'. Over the years, CA has certainly 'branched out' from those roots.
McHoul, A.
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source